More than Half of Patients with Schizophrenia Are Receiving Polypharmacy and Co-Prescription of Anxiolytics in Pakistan —Findings from Research on Asian Prescription Pattern in 2016

Autor:	Mazhar Malik, Masaki Shinfuku, Shu Yu Yang, Mian-Yoon Chong, Munir Hamirani, Usman Ghani, Shih-Ku Lin, Winston W. Shen, Naotaka Shinfuku, Sandeep Grover, Liang-Yu Chen, Nasar Sayeed Kahn, Afzal Javed, Norman Sartorius, Nargis Munir, Chay Hoon Tan, Nariman Awais
Rok vydání:	2018
Předmět:	Polypharmacy medicine.medical_specialty business.industry medicine.medical_treatment Guideline medicine.disease Psychotropic drug Mood Pharmacotherapy Schizophrenia Family medicine medicine Medical prescription business Antipsychotic
Zdroj:	Open Journal of Psychiatry. :199-211
ISSN:	2161-7333 2161-7325
Popis:	Objective: Little is known about the prescription pattern of psychotropic drugs for patients with schizophrenia in Pakistan. The purpose of this study was to evaluate the characteristic features of psychotropic drug prescriptions for patients with schizophrenia in Pakistan. Methods: Three centers in Pakistan participated in a large scale collaborative study known as Research on Asian Prescription Pattern (REAP). The 2016 REAP survey included centers from 15 countries in Asia and used a unified research protocol. The design of the study was quantitative and of descriptive epidemiology. Analysis was made on the data collected from three centers i.e., Lahore, Karachi and Islamabad. The data collected in Pakistan were compared with those from other Asian countries. The details of REAP were presented on the homepage of REAP (http://www.REAP.Asia). Results: From Pakistan, 298 patients were included. Patients with schizophrenia in Pakistan received higher rate of antipsychotic polypharmacy and a higher rate of co-prescription of mood stabilizers and anxiolytics when compared with participants from other South Asian countries (India and Bangladesh). Conclusion: The main findings of the study were that a majority of the patients were prescribed antipsychotic polypharmacy drugs in Pakistan. Insufficient training on the use of psychotropic drugs and a lack of treatment guideline are considered to be the major contributing factors. Further education and training on the proper use of psychotropic drugs are recommended to psychiatrists in Pakistan. The guidelines on pharmacotherapy for patients with schizophrenia should also be developed and promoted in Pakistan.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2ac3a9fc36b9de782cc97d677a8a88e7 https://doi.org/10.4236/ojpsych.2018.83018 Zobrazit plný text záznamu