Radical cyclisation mediates the synthesis of a new base-ribose carbon bridged adenosine

Autor:	Pierre Joseph Marcel Jung, Jean-François Biellmann, Alain Burger, Pascal Lang, Alain Mayer, Denis Tritsch
Rok vydání:	2004
Předmět:	chemistry.chemical_classification Base (chemistry) Stereochemistry Organic Chemistry chemistry.chemical_element Tributyltin hydride Biochemistry Adenosine chemistry.chemical_compound chemistry Yield (chemistry) Drug Discovery Ribose medicine Nucleoside Carbon medicine.drug
Zdroj:	Tetrahedron Letters. 45:4013-4015
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2004.03.176
Popis:	Reaction of tributylstannyl, radical generated in situ with AIBN, with (2′,5′-di-O- tert -butyldimethylsilyl-3′-C-ethynyl-β- d - ribo -furanosyl)adenine ( 5 ) gave in 69% yield the new conformationally locked nucleosides 6 ( E/Z ).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2ab76a215e25647d1ca961325e58a278 https://doi.org/10.1016/j.tetlet.2004.03.176 Zobrazit plný text záznamu Full Text from ScienceDirect