Binding to the conserved and stably folded guide RNA pseudoknot induces Cas12a conformational changes during ribonucleoprotein assembly

Autor: Sruthi Sudhakar, Christopher L. Barkau, Ramadevi Chilamkurthy, Halle M. Barber, Adrian A. Pater, Sean D. Moran, Masad J. Damha, P.I. Pradeepkumar, Keith T. Gagnon
Rok vydání: 2023
Předmět:
Zdroj: Journal of Biological Chemistry. 299:104700
ISSN: 0021-9258
Databáze: OpenAIRE