Reptilia: Humoral Immunity in Reptiles
Autor: | Laura M. Zimmerman |
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Rok vydání: | 2018 |
Předmět: |
0106 biological sciences
0301 basic medicine Squamata biology Tuatara Zoology Context (language use) biology.organism_classification 010603 evolutionary biology 01 natural sciences Crocodilia 03 medical and health sciences 030104 developmental biology Immune system Ectotherm Humoral immunity biology.protein Antibody |
Zdroj: | Advances in Comparative Immunology ISBN: 9783319767673 |
DOI: | 10.1007/978-3-319-76768-0_20 |
Popis: | Reptiles are a diverse group which include four orders: Crocodilia, Testudines, Tuatara, and Squamata. Though they differ greatly in a number of characteristics, they tend to use their humoral immune response in a similar manner. Compared to mammals, reptiles tend to have a slower and less robust humoral immune response. Reptiles may instead rely on a non-specific component of the humoral immune response: natural antibodies. Phagocytic B cells have also been identified in reptiles, and further studies are needed to explore this additional innate-like function of the humoral response in a variety of reptiles. Because reptiles are ectothermic, temperature can impact their immune responses both during development and as adults. Their immune system is also strongly affected by season. In addition, because reptiles typically have long life spans and can have indeterminate growth, they are an intriguing taxon in which to study aging. Life-history characteristics of reptiles provide many possibilities for understanding the context in which the immune strategy of reptiles evolved and how they may respond to climate change and disease introduction. |
Databáze: | OpenAIRE |
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