| Autor: |
Mitsuru Amanuma, Tatsuo Shirai, Takeshi Morishita, Jun-ichi Hirai, Susumu Hasegawa, Nichizo Koizumi, Toru Shindo, Koya N, Shinichiro Suzuki |
| Rok vydání: |
1977 |
| Předmět: |
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| Zdroj: |
VIth International Congress on Thrombosis and Haemostasis. |
| ISSN: |
2567-689X |
| Popis: |
It is known that coronary thrombosis is found in most cases of myocardial infarction. There is surely relationship between the infarction and thrombosis. Platelet aggregation and fibrin formation mechanism are of course concerned with the thrombosis, but the purpose of our research is to know how fibrin stabilizing factor is involved in that. From this respect, we observed the behavior of F.S.F. in myocardial infarction. The typical changing pattern of plasma F.S.F. in the myocardial infarction is as follows; it holds high level just after the onset, rapidly decreases right after, goes down to the minimum at 5th - 7th day, gradually increases thereafter, returns to normal level at about 14th day. This profile was almost same as that in case of experimental myocardial infarction in dogs and was very specific in heart tissue, but was not observed in the control surgical experiment, and in the patients with brain bleeding and thrombosis. The experiment of Master’s two-step test to see the effect on plasma F.S.F. level gave an interesting result. The tests of about 100 normal plasma showed the age dependency which means the increasing F.S.F. concentration in plasma related on age. The mean of F.S.F. in adult was 21±3 (μM MDC/10 min). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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