Peptide Bond-Forming Reaction via Amino Acid Silyl Esters: New Catalytic Reactivity of an Aminosilane

Autor:	Hisashi Yamamoto, Chaitanya Manthena, Erika Nakashima, Wataru Muramatsu
Rok vydání:	2020
Předmět:	chemistry.chemical_classification Silylation 010405 organic chemistry Stereochemistry Peptide General Chemistry 010402 general chemistry 01 natural sciences Catalysis 0104 chemical sciences Amino acid chemistry Peptide bond Reactivity (chemistry)
Zdroj:	ACS Catalysis. 10:9594-9603
ISSN:	2155-5435
Popis:	The epimerization-free formation of peptide bonds is crucial for the development of peptide therapeutics and pharmaceuticals. Herein, we report a hydrosilane-mediated approach for the construction ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2a9093d0efd32e473d9a0b56d7d3b091 https://doi.org/10.1021/acscatal.0c02512 Zobrazit plný text záznamu