Muscle mass as a target to reduce fatigue in patients with advanced cancer
| Autor: | Marian A. E. de van der Schueren, Annemarie Becker-Commissaris, Maurice J. D. L. van der Vorst, Laurien M. Buffart, Susanne Blauwhoff-Buskermolen, Renske M. van den Hurk, Elisabeth C. W. Neefjes, Henk M.W. Verheul |
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| Rok vydání: | 2017 |
| Předmět: |
Oncology
medicine.medical_specialty Palliative care business.industry Confounding Skeletal muscle Cancer 030204 cardiovascular system & hematology medicine.disease 03 medical and health sciences Prostate cancer 0302 clinical medicine medicine.anatomical_structure Quality of life Interquartile range 030220 oncology & carcinogenesis Physiology (medical) Internal medicine medicine Physical therapy Orthopedics and Sports Medicine medicine.symptom business Cancer-related fatigue |
| Zdroj: | Journal of Cachexia, Sarcopenia and Muscle. 8:623-629 |
| ISSN: | 2190-5991 |
| Popis: | Background Cancer-related fatigue (CRF) reduces quality of life and the activity level of patients with cancer. Cancer related fatigue can be reduced by exercise interventions that may concurrently increase muscle mass. We hypothesized that low muscle mass is directly related to higher CRF. Methods A total of 233 patients with advanced cancer starting palliative chemotherapy for lung, colorectal, breast, or prostate cancer were studied. The skeletal muscle index (SMI) was calculated as the patient's muscle mass on level L3 or T4 of a computed tomography scan, adjusted for height. Fatigue was assessed with the Functional Assessment of Chronic Illness Therapy-fatigue questionnaire (cut-off for fatigue |
| Databáze: | OpenAIRE |
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