Differences in Sensory Thresholds in the Skin of Women with Fibromyalgia Syndrome: A Comparison Between Ketamine Responders and Ketamine Non-Responders

Autor:	Sally Aspegren Kendall, Björn Gerdle, Ann Bengtsson, Ingrid Hurtig, Birgitta Sören, K. G. Henriksson, Ragnhild Raak, Lis Karin Wahren
Rok vydání:	2003
Předmět:	integumentary system business.industry medicine.disease Blockade Non responders Allodynia Fibromyalgia syndrome Rheumatology Anesthesia Sensory threshold Fibromyalgia Sensation Medicine Ketamine medicine.symptom business medicine.drug
Zdroj:	Journal of Musculoskeletal Pain. 11:3-9
ISSN:	1540-7012 1058-2452
DOI:	10.1300/j094v11n02_02
Popis:	Objectives: To compare detection and pain thresholds in the skin of female fibromyalgia patients who were either ketamine responders or ketamine nonresponders.Methods: Detection thresholds to innocuous warmth, of cold, heat or cold pain, and touch and dynamic touch sensation were determined in the skin. Pressure pain thresholds, local and widespread pain intensity, and pain duration were also registered.Results: Ketamine nonresponse was associated with more pronounced hypersensitivity for thermal pain [especially cold pain] than ketamine response.Conclusions: Blockade of N-metyl-D-aspartic acid receptors by ketamine and the recording of pain thresholds in the skin, especially for cold pain, might reveal different mechanisms of allodynia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2a810145d5368b1d0e248f7e00c49042 https://doi.org/10.1300/j094v11n02_02 Zobrazit plný text záznamu Plný text ve formátu PDF