TCR inhibitory molecule as a promising allogeneic NKG2D CAR-t cell approach
Autor: | Céline Jacques-Hespel, Sophie Agaugue, Nancy Ramelot, Julien Houssa, David E. Gilham, Jennifer Bolsée, Eytan Breman, Sébastien Mauen, Benjamin Violle, Céline Marchand, Alexandre Michaux, Thuy Nguyen, Jérôme Marijsse, Fanny Huberty |
---|---|
Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Cancer Research Autologous cell business.industry T-cell receptor NKG2D Inhibitory postsynaptic potential 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Oncology 030220 oncology & carcinogenesis Cancer research Medicine CAR T-cell therapy Healthy donor Car t cells business |
Zdroj: | Journal of Clinical Oncology. 36:e15042-e15042 |
ISSN: | 1527-7755 0732-183X |
Popis: | e15042Background: Most CAR T cell therapy relies on autologous cells with potential limitation in quality of the cells. Cells derived from an allogeneic healthy donor may be more consistent in qual... |
Databáze: | OpenAIRE |
Externí odkaz: |