Influence of cerebral white matter hyperintensities on cognitive impairment in elderly medical patients
| Autor: | Yoshiko Nishimura, Kuniaki Otsuka, Hiroshi Sakura, Koichi Shibata |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Mini–Mental State Examination 030214 geriatrics medicine.diagnostic_test business.industry medicine.disease Hyperintensity White matter 03 medical and health sciences 0302 clinical medicine Atrophy medicine.anatomical_structure Internal medicine Physical therapy Medicine Geriatric Depression Scale Cognitive decline business Stroke 030217 neurology & neurosurgery Kidney disease |
| Zdroj: | Geriatrics & Gerontology International. 17:1488-1493 |
| ISSN: | 1444-1586 |
| DOI: | 10.1111/ggi.12900 |
| Popis: | Aim We investigated the characteristics of elderly medical patients with white matter hyperintensities on magnetic resonance imaging. Methods A total of 213 patients (123 men and 90 women; mean age 74.8 years) reported their history of hypertension, diabetes, dyslipidemia, previous stroke, coronary heart disease and chronic kidney disease (CKD). All patients completed the Mini-Mental State Examination and Geriatric Depression Scale. White matter hyperintensities were evaluated for the periventricular region, basal ganglia (BGH), deep white matter and infratentorial region, and brain atrophy was calculated as bicaudate ratios. Results Patients with cognitive impairment (Mini-Mental State Examination score |
| Databáze: | OpenAIRE |
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