| Popis: |
There are at least two measurements of tumor aggressiveness that we can obtain using DNA flow cytometry techniques. One is the estimate of ploidy status or DNA content of a patient’s tumor, usually referred to as DNA diploid, if the tumor contains a normal amount of DNA, or DNA aneuploid, if the tumor contains an abnormal amount of DNA (hypo or hyperdiploid). The other prognostic factor is an estimate of a tumor’s proliferative capacity, obtained by measuring the percentage of nuclei in the DNA synthetic phase (S phase) of the cell cycle. The S phase is usually referred to as “high” or “low” (and sometimes intermediate), often based on a mean or median value obtained from a large database. |
