Pulsed Carbon Dioxide Laser, Trichloroacetic Acid, Baker-Gordon Phenol, and Dermabrasion: A Comparative Clinical and Histologic Study of Cutaneous Resurfacing in a Porcine Model
| Autor: | Nancy M. Satur, Richard E. Fitzpatrick, Mitchel P. Goldman, Whitney D. Tope |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
business.industry Dermabrasion medicine.medical_treatment Dermatology General Medicine Carbon dioxide laser Laser Surgery law.invention chemistry.chemical_compound chemistry law Vaporization medicine Phenol Animal study Trichloroacetic acid Wound healing business Biomedical engineering |
| Zdroj: | Archives of Dermatology. 132:469 |
| ISSN: | 0003-987X |
| DOI: | 10.1001/archderm.1996.03890280135023 |
| Popis: | Recent advancements in carbon dioxide laser technology have allowed the development of microsecond-domain pulses with a high pulse energy (up to 500 mJ), enabling precise and complete tissue vaporization while minimizing residual thermal damage and its potential adverse effects on wound healing. 1 For appropriate clinical application, one should know the depth of vaporization and residual thermal damage after successive laser passes over the same area, the depth of vaporization and residual thermal damage caused by different pulse energies, and how these in turn compare with the depth of tissue removal afforded by currently used resurfacing modalities: dermabrasion, 35% trichloroacetic acid peel, and Baker-Gordon (50%) phenol peel. To evaluate these immediate tissue effects and postoperative wound healing for all of these modalities, a clinical and histologic animal study was performed. Materials and Methods. A grid that delineated 16 treatment sites measuring 3×3 cm was tattooed onto the paravertebral area of |
| Databáze: | OpenAIRE |
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