Toxoplasmoses Congenitales et Seroconversions De Fin De Grossesse: Observations Cliniques
| Autor: | Y Bietlot, L Fiasse, O. Bauraind, V. Luyasu, P Bernard, C Brasseur, E Longueville, M. Michel, M Wacquez, J L Melard, J Englebert, O Givron |
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| Rok vydání: | 1997 |
| Předmět: |
Gynecology
Pregnancy medicine.medical_specialty business.industry Sulfamethoxazole General Medicine medicine.disease Trimethoprim Toxoplasmosis 03 medical and health sciences 0302 clinical medicine Pyrimethamine Sulfadiazine 030220 oncology & carcinogenesis Immunology medicine 030212 general & internal medicine Seroconversion business medicine.drug Subclinical infection |
| Zdroj: | Acta Clinica Belgica. 52:381-387 |
| ISSN: | 2295-3337 1784-3286 |
| DOI: | 10.1080/17843286.1997.11718604 |
| Popis: | We report seven cases of subclinical congenital toxoplasmosis secondary to maternal primary infections. Mothers were infected between two and four weeks prior to delivery. The diagnostic criteria of congenital infections included: IgM antibody (Ab) (1 case); IgM and IgA Ab (1 case); a real IgG seroconversion in the neonatal and postnatal samples (3 cases); persistence of IgG Ab beyond 6 months post-delivery (2 cases). A treatment was initiated, including a combination of pyrimethamine + sulfadiazine (6 cases); trimethoprim + sulfamethoxazole (1 case). This retrospective study suggests that it is important to screen the non-immune pregnant women until delivery. We confirmed the usefulness of a combination of isotypes of antibodies for the accurate assessment of congenital infection. Finally, infected infants have to be treated and monitored clinically and immunologically during the first year of life. |
| Databáze: | OpenAIRE |
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