Comparative estimation of the EGFP effects on the development of embryos obtained by reciprocal crossing of C57BL/6-Tgn(ACTbEGFP)1Osb/J and C57BL/6 mice
Autor: | A. A. Smirnov, L. M. Mezhevikina, N. Yu. Sakharova, L. A. Fialkovskaya, D. V. Stasenko |
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Rok vydání: | 2011 |
Předmět: | |
Zdroj: | Russian Journal of Genetics. 47:726-731 |
ISSN: | 1608-3369 1022-7954 |
DOI: | 10.1134/s1022795411050139 |
Popis: | The effect of enhanced green fluorescent protein (EGFP) on the in vitro viability of early embryos of C57BL/6-Tgn(ACTbEGFP)1Osb/J mice has been studied. The number of viable ova in hemizygous females (−/egfp) has been shown to decrease. Irrespective of the EGFP level, it has no deleterious effect on the early development of embryos obtained by reciprocal crossing of hemizygous (−/egfp) and wild-type (−/−) mice. |
Databáze: | OpenAIRE |
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