Comparative estimation of the EGFP effects on the development of embryos obtained by reciprocal crossing of C57BL/6-Tgn(ACTbEGFP)1Osb/J and C57BL/6 mice

Autor: A. A. Smirnov, L. M. Mezhevikina, N. Yu. Sakharova, L. A. Fialkovskaya, D. V. Stasenko
Rok vydání: 2011
Předmět:
Zdroj: Russian Journal of Genetics. 47:726-731
ISSN: 1608-3369
1022-7954
DOI: 10.1134/s1022795411050139
Popis: The effect of enhanced green fluorescent protein (EGFP) on the in vitro viability of early embryos of C57BL/6-Tgn(ACTbEGFP)1Osb/J mice has been studied. The number of viable ova in hemizygous females (−/egfp) has been shown to decrease. Irrespective of the EGFP level, it has no deleterious effect on the early development of embryos obtained by reciprocal crossing of hemizygous (−/egfp) and wild-type (−/−) mice.
Databáze: OpenAIRE