| Autor: |
Zheng Fang, Mixue Bian, Jia Xu, Yang Lin, Wei He, Chengkou Liu, Jiawei Hua, Zhao Yang, Li Yuguang, Kai Guo |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Organic Chemistry Frontiers. 7:3223-3228 |
| ISSN: |
2052-4129 |
| DOI: |
10.1039/d0qo00909a |
| Popis: |
An efficient and green electrochemical continuous-flow approach has been developed for the synthesis of 4-(sulfonylmethyl)isoquinoline-1,3(2H,4H)-diones through the sulfonylation of alkenes with sulfonylhydrazides. The reaction proceeds in a continuous-flow electrolytic cell under metal-free and oxidant-free conditions. A series of activated alkenes were suitable for this system, and the corresponding products were obtained in moderate to good yields. Moreover, reaction scale-up was smoothly achieved using the electrochemical continuous-flow system without changing the reaction conditions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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