One-pot Three-component Synthesis of Furan-based Heterocycles from Benzyl Halides

Autor:	Mallappa Beerappa, Kalegowda Shivashankar
Rok vydání:	2017
Předmět:	010405 organic chemistry Component (thermodynamics) Isocyanide Organic Chemistry Halide 010402 general chemistry 01 natural sciences Cycloaddition 0104 chemical sciences Turn (biochemistry) chemistry.chemical_compound chemistry Furan Yield (chemistry) Organic chemistry
Zdroj:	Journal of Heterocyclic Chemistry. 54:2197-2205
ISSN:	0022-152X
DOI:	10.1002/jhet.2806
Popis:	An efficient and a novel approach for the synthesis of furochromene and furopyran scaffolds are described. Benzyl halides undergo oxidation in Kornblum conditions to give the corresponding aldehydes, which in turn undergo 4 + 1 cycloaddition reaction with isocyanide to afford the corresponding furan derivatives. The significant attraction of this protocol is simple procedure, mild reaction condition, and good yield. © 2017 Wiley Periodicals, Inc.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2a2f03a07a74795101dc3079bd5b3781 https://doi.org/10.1002/jhet.2806 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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