Effect of tryptophan deficiency on bones and teeth of rats

Autor: Lucien A. Bavetta, Sol Bernick
Rok vydání: 1956
Předmět:
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology. 9:308-315
ISSN: 0030-4220
Popis: A study was made of the histologic changes occurring in the long bones and the alveolar bone of rats maintained on a tryptophan-deficient diet for periods of time varying from three to twenty-six weeks. A narrowing and premature closure of the epiphyseal plate were noted after five weeks on the deficient diet. This closure prevented further growth of the animal. The osteoporosis of the long bones was progressive in nature, becoming intense in those animals on the deficient diet for sixteen to twenty-six weeks. There was a gradual replacement of the myeloid elements of the marrow spaces by fatty tissues. The osteoporosis of the spongiosa of the alveolar bone was a constant finding. As a result of this osteoporosis, the bone was unable to cope with the normal stresses usually imposed upon it, leading to secondary occlusal trauma.
Databáze: OpenAIRE