ChemInform Abstract: Cinchona Alkaloid Amide Catalyzed Enantioselective Formal [2 + 2] Cycloadditions of Allenoates and Imines: Synthesis of 2,4-Disubstituted Azetidines

Autor:	J. M. Denis, Jieping Zhu, Pascal Retailleau, Géraldine Masson
Rok vydání:	2011
Předmět:	Quinidine biology Enantioselective synthesis Cinchona General Medicine biology.organism_classification Cycloaddition Catalysis chemistry.chemical_compound chemistry Organocatalysis Amide medicine Organic chemistry Bifunctional medicine.drug
Zdroj:	ChemInform. 42
ISSN:	0931-7597
DOI:	10.1002/chin.201140100
Popis:	Asymmetric formal [2 + 2] cycloaddition of N-sulfonylimines (I) and (IV) with allenoates (II) is efficiently catalyzed by a bifunctional glycinamide-containing quinidine organocatalyst to give azetidines (III) and (V), resp., in high enantioselectivity (up to 98% e.e.).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2a22f0c0009db9bea7d6b29ae85d799c https://doi.org/10.1002/chin.201140100 Zobrazit plný text záznamu Plný text