ASYMPTOMATIC TRANSIENT SA-NODE CONDUCTION BLOCK IN A PATIENT WITH ACUTE RISPERIDONE+TRIHEXYPHENYDYL TABLET POISONING

Autor: Shyojiram Meena Dr, Dhiresh Salvi Dr, Varun Kumar M C Dr, Pramod Chaurasiya Dr
Rok vydání: 2021
Předmět:
Zdroj: PARIPEX INDIAN JOURNAL OF RESEARCH. :23-24
DOI: 10.36106/paripex/1602917
Popis: BACKGROUND: a case report of 17year old male with acute risperidone + trihexyphenidyl poisoning with transient sinoatrial block without any CNS or neuromuscular complications. CONCLUSION: Risperidone does possess cardiotoxicity as of cardiac conduction abnormalities mainly affecting SA 1 and AV nodes rather than prolongation of QT interval without causing hypotension or myocardial injury . Such a nonlethal conduction aberrancy was observed at a dose of 75mg risperidone was only transient and reversed physiologically without any additional treatment. Further protection from extrapyramidal symptoms was offered by combined drug trihexyphenidyl at cost of sedation.
Databáze: OpenAIRE