Combined Amphotericin B-Flucytosine Therapy in Aspergillus Pneumonia

Autor:	Mary Hannigan, Stephen D. Codish, Jeffrey S. Tobias
Rok vydání:	1979
Předmět:	medicine.medical_specialty Combination therapy medicine.drug_class business.industry Antibiotics General Medicine Aspergillosis medicine.disease Gastroenterology Flucytosine Pneumonia Pharmacotherapy Amphotericin B Internal medicine Toxicity medicine Intensive care medicine business medicine.drug
Zdroj:	JAMA: The Journal of the American Medical Association. 241:2418
ISSN:	0098-7484 2418-2419
DOI:	10.1001/jama.1979.03290480052025
Popis:	The incidence of aspergillosis is increasing while the prognosis remains dismal. Standard single-drug therapy with amphotericin B offers unacceptably low cure rates. A patient withAspergilluspneumonia was treated with a synergistic combination of amphotericin B and flucytosine. A prompt clinical response and progressive resolution of the infection were observed. Combination therapy appeared to decrease the dose of amphotericin B needed for effective therapy. It may provide improved results with decreased toxic effects. (JAMA241:2418-2419, 1979)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2a15e326fc9410e6fd1d754f4b4fe333 https://doi.org/10.1001/jama.1979.03290480052025 Zobrazit plný text záznamu