Treatment of Advanced Heart Failure—Focus on Transplantation and Durable Mechanical Circulatory Support

Autor: Frank Ruschitzka, Mateusz Sokolski, Markus J. Wilhelm, Stephan Winnik, Fran Mikulicic, Raed Aser, Federica Guidetti, Michelle Frank, Mattia Arrigo, Andreas J. Flammer
Rok vydání: 2021
Předmět:
Zdroj: Heart Failure Clinics. 17:697-708
ISSN: 1551-7136
Popis: Heart transplantation (HTx) is the treatment of choice in patients with late-stage advanced heart failure (Advanced HF). Survival rates 1, 5, and 10 years after transplantation are 87%, 77%, and 57%, respectively, and the average life expectancy is 9.16 years. However, because of the donor organ shortage, waiting times often exceed life expectancy, resulting in a waiting list mortality of around 20%. This review aims to provide an overview of current standard, recent advances, and future developments in the treatment of Advanced HF with a focus on long-term mechanical circulatory support and HTx.
Databáze: OpenAIRE