Dosimetric impact of applicator displacement during high dose rate (HDR) Cobalt-60 brachytherapy for cervical cancer: A planning study
| Autor: | Jeannie Hsiu Ding Wong, Zulaikha Jamalludin, Kwan Hoong Ng, Rozita Abdul Malik, Yih Miin Liew, J.S. Yong, Ngie Min Ung |
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| Rok vydání: | 2016 |
| Předmět: |
Cervical cancer
Radiation Cobalt 60 brachytherapy business.industry medicine.medical_treatment Brachytherapy medicine.disease High-Dose Rate Brachytherapy 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Planning study medicine Displacement (orthopedic surgery) business Nuclear medicine Dose rate Radiation treatment planning |
| Zdroj: | Radiation Physics and Chemistry. 119:264-271 |
| ISSN: | 0969-806X |
| DOI: | 10.1016/j.radphyschem.2015.11.011 |
| Popis: | We investigated the dosimetric impact of applicator displacement on dose specification during high dose rate (HDR) Cobalt-60 (Co-60) brachytherapy for cervical cancer through a planning study. Eighteen randomly selected HDR full insertion plans were restrospectively studied. The tandem and ovoids were virtually shifted translationally and rotationally in the x-, y- and z-axis directions on the treatment planning system. Doses to reference points and volumes of interest in the plans with shifted applicators were compared with the original plans. The impact of dose displacement on 2D (point-based) and 3D (volume-based) treatment planning techniques was also assessed. A ±2 mm translational y-axis applicator shift and ±4° rotational x-axis applicator shift resulted in dosimetric changes of more than 5% to organs at risk (OAR) reference points. Changes to the maximum doses to 2 cc of the organ (D2cc) in 3D planning were statistically significant and higher than the reference points in 2D planning for both the rectum and bladder (p |
| Databáze: | OpenAIRE |
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