EVALUATION OF IN VITRO ANTIOXIDANT AND IN VIVO HEPATOPROTECTIVE ACTIVITY OF BAUHINIA VARIEGATA ROOT ETHANOLIC EXTRACT AGAINST CCL4 INDUCED LIVER INJURY IN RATS

Autor: GANESH PAWAR
Rok vydání: 2021
Předmět:
Zdroj: INDIAN DRUGS. 58:60-65
ISSN: 0019-462X
DOI: 10.53879/id.58.11.12859
Popis: Plant derived herbal formulations and remedies provide an effective means for the treatment of various types of disease that are dogmatic and incurable in other types of systems of medicines, but it is essential to explore and establish the scientific basis for therapeutic action of herbal plant medicines. Bauhinia variegata root ethanolic extract was studied for the hepatoprotective activity against CCl4 induced liver injury in rats. For estimation of hepatoprotective role of B. variegata, total bilirubin count, serum enzymes level and finally histopathological study of liver were performed. This extract’s DPPH radical scavenging potential was also studied. The ethanolic extract of B. variegata root administered orally to animal showed significant depletion in CCL4 induced increased level of SGPT, SGOT, ALP and total bilirubin concentration. Significantly (p
Databáze: OpenAIRE