Morphological changes of mucosa in gastric bladders after long term follow up
| Autor: | John H. K. Ngan, M.K. Li, Kwan-Hon Chan |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
Pathology Urinary bladder Long term follow up business.industry Stomach Intestinal metaplasia medicine.disease Gastroenterology digestive system diseases Pathology and Forensic Medicine medicine.anatomical_structure Atrophy Fundus (uterus) Metaplasia Internal medicine medicine Carcinoma medicine.symptom business |
| Zdroj: | Pathology. 22:2 |
| ISSN: | 0031-3025 |
| DOI: | 10.1016/s0031-3025(16)36312-7 |
| Popis: | The body and fundus of the stomach were used to restore the capacity of diseased urinary bladder in 8 patients. Gastric bladder biopsies were taken 4 to 14 years (mean 9.7 years) after the operation and studied with light and transmission electron microscopes. The findings varied from near normal fundic mucosa to moderate atrophy and severe active chronic inflammatory changes. Pyloric metaplasia was present in 2 gastric bladders and intestinal metaplasia was observed in another one. Dysplastic changes were not seen. The finding of essentially normal fundic mucosa in 3 gastric bladders which had functioned for 4 to 14 years showed that gastric fundic mucosa was stable when constantly bathed by urine. The absence of dysplastic changes but the presence of intestinal metaplasia in the gastric bladders suggested that the risk of carcinoma developing was low. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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