Win 70197: a novel liver-targeted magnetic resonance imaging contrast agent
| Autor: | E. Liversidge, J. L. Toner, J. Shen, Kenneth E. Kellar, David L. Ladd, T.J. Caulfied, C. R. Illig, Jennifer Wellons, P. Guo, N. Peltier |
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| Rok vydání: | 1995 |
| Předmět: |
Toxicity data
medicine.diagnostic_test Stereochemistry media_common.quotation_subject Gadolinium MRI contrast agent Organic Chemistry Clinical Biochemistry Pharmaceutical Science chemistry.chemical_element Magnetic resonance imaging Biochemistry Nuclear magnetic resonance chemistry Drug Discovery medicine Molecular Medicine Contrast (vision) Chelation Molecular Biology media_common |
| Zdroj: | Bioorganic & Medicinal Chemistry Letters. 5:1657-1662 |
| ISSN: | 0960-894X |
| Popis: | WIN 70197 is a novel liver-targeted MRI contrast agent. This report describes the efficient synthesis of the chelator along with preliminary NMRD and toxicity data of the gadolinium complex. X-ray diffraction data was used to confirm the predicted chelate structure. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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