Incidence, predictors and outcomes of cardiovascular events in patients with chronic lymphocytic leukemia

Autor: Ghulam Ghous, Nanuli Gvazava, Peter Egwom, Mohammad Saleh, Diana Franco, Hafiz Muhammad Hassan Shoukat, Pak Ho Au, Kelechi Nwabara, Zahid Tarar
Rok vydání: 2022
Předmět:
Zdroj: Journal of Clinical Oncology. 40:e19524-e19524
ISSN: 1527-7755
0732-183X
Popis: e19524 Background: CLL accounts for about one-quarter of the new cases of leukemia and affects mainly elderly population. Recent literature highlights increased cardiovascular events in patients with CLL, notably those being treated with targeted therapy such as Bruton tyrosine kinase inhibitors. Here we examine data obtained from the National Inpatient Sample to find out incidence, predictors and outcomes of cardiovascular events in patients with CLL. Methods: We analyzed the National inpatient database from year 2019 and extracted the data of all patients with CLL. Multivariate regression analysis was performed to determine the aforementioned outcomes in CLL patients. Results: CLL patients showed increased odds of all cause in-hospital mortality (Adjusted Odds ratio (AOR) 1.28, 95% CI 1.19-1.38, P
Databáze: OpenAIRE