Noninvasive prenatal testing in women undergoing in vitro fertilization with preimplantation genetic testing
| Autor: | Richard T. Scott, Amber M Klimczak, Emre Seli |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
education.field_of_study Pregnancy 030219 obstetrics & reproductive medicine In vitro fertilisation medicine.diagnostic_test Obstetrics business.industry medicine.medical_treatment Population Obstetrics and Gynecology Aneuploidy medicine.disease Predictive value 03 medical and health sciences 0302 clinical medicine Prenatal screening 030220 oncology & carcinogenesis embryonic structures medicine Positive test education business Genetic testing |
| Zdroj: | Current Opinion in Obstetrics & Gynecology. 33:184-187 |
| ISSN: | 1473-656X 1040-872X |
| DOI: | 10.1097/gco.0000000000000707 |
| Popis: | Purpose of review To discuss the utilization, performance, and interpretation of noninvasive prenatal testing (NIPT) results in women achieving pregnancy through in vitro fertilization (IVF) and preimplantation genetic testing for aneuploidy (PGT-A). Recent findings Although PGT-A is a highly accurate method for the selection of euploid embryos the possibility for error still exists. Many women pursue NIPT after conception via IVF with or without PGT-A, whereas some forgo prenatal screening all together. Recent evidence suggests that the prevalence of a positive NIPT following PGT-A is low, and the positive predictive value is altered in this population. Summary NIPT is a valuable prenatal screening tool that should be offered to pregnant women regardless of prior PGT. In women who conceive following IVF and PGT-A through the transfer of euploid embryos, positive test results should be interpreted with caution. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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