An XDR Pseudomonas aeruginosa ST463 Strain with an IncP-2 Plasmid Containing a Novel Transposon Tn 6485f Encoding bla IMP-45 and bla AFM-1 and a Second Plasmid with Two Copies of bla KPC-2

Autor: Yinfei Fang, Nanfei Wang, Zhaoxia Wu, Yijun Zhu, Yongjun Ma, Yue Li, Heng Cai, Piaopiao Zhang, Sebastian Leptihn, Yunsong Yu, Xiaoting Hua, Yuexing Tu
Rok vydání: 2023
Předmět:
Zdroj: Microbiology Spectrum. 11
ISSN: 2165-0497
DOI: 10.1128/spectrum.04462-22
Popis: The ST463 clone is an emerging high-risk sequence type that is spreading with bla KPC-2 -containing plasmids. The core bla KPC-2 genetic platform is IS Kpn27 -b la KPC-2 -IS Kpn6 in almost all samples, and the adjacent region beyond the core platform varies by IS 26 -mediated inversion or duplication events, amplifying the bla KPC-2 gene copies.
Databáze: OpenAIRE