Effect of acclimation of rainbow trout (Salmo gairdneri) to arsenic on retention of a subsequent dose of arsenic
| Autor: | A. S. W. deFreitas, S.U. Qadri, A. A. Oladimeji |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
biology
Health Toxicology and Mutagenesis Public Health Environmental and Occupational Health chemistry.chemical_element General Medicine Fractional clearance biology.organism_classification Pollution Acclimatization Arsenic acid Toxicology Trout chemistry.chemical_compound Animal science chemistry Excretory system Rainbow trout Salmo Arsenic |
| Zdroj: | Ecotoxicology and Environmental Safety. 6:196-203 |
| ISSN: | 0147-6513 |
| DOI: | 10.1016/0147-6513(82)90010-0 |
| Popis: | A dose of 10 ng As/100 g 74As-labeled arsenic acid was given in the diet to three groups of rainbow trout. These groups consisted of the control (maintained under identical conditions in the absence of arsenic) and two groups preexposed to 5.7 and 22.8 mg As/kg diet for 2 weeks, respectively. The elimination rate of arsenic (74As) was determined by whole-body counting of the live fish for 16 days in a gamma spectrophotometer. Elimination of arsenic by rainbow trout was biphasic in all groups. Clearance of the subsequent dose of 74As in trout preexposed to 5.7 mg As/kg diet for 2 weeks was similar to that of the control. However, fish preexposed to 22.8 mg As/kg diet for the same period, prior to the administration of 74As, demonstrated a significantly higher (P < 0.05) fractional clearance rate of 0.22 day−1 for the slow-clearing compartment compared to the rate of 0.11 day−1 in the control. Half-lives of elimination were 6.4, 6.2, and 3.2 days for the slow-clearing phase of the control, the 5.7, and 22.8 mg As/kg diet groups, respectively. The decreased retention of the subsequent dose of arsenic (74As) is interpreted as evidence of an increase in the capacity of the excretory mechanisms of arsenic due to preexposure. |
| Databáze: | OpenAIRE |
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