| Autor: |
Tetiana Bogdanova, Victor Shpak, Valeriy Oliynyk, Liudmyla Yu Zurnadzhy, Stephen J. Chanock, Alina V. Brenner, Mark P. Little, I. A. Likhtarev, Vladimir Drozdovitch, Galyna Zamotayeva, André Bouville, Mykola Tronko, Valeriy Tereshchenko, Kiyohiko Mabuchi, Maureen Hatch |
| Rok vydání: |
2017 |
| Předmět: |
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| Popis: |
The Ukrainian–American (UkrAm) thyroid study is a cohort study of thyroid cancer and other thyroid pathologies in Ukrainian individuals exposed as children or adolescents to radioactive fallout from the Chernobyl accident. The 13,243 cohort members with direct thyroid radioactivity measurements taken in May–June 1986 were first screened in 1998–2000. During the period 2001–07, three additional biennial cycles of thyroid screening examinations were carried out. A fifth screening was conducted between 2012 and 2015, with 76.4% of the original cohort coming for examinations. As a result of this latest screening, 47 new pathologically confirmed thyroid cancers were diagnosed by the end of 2015. Preliminary analyses of the fifth cycle data show a statistically significant excess of radiation-related thyroid cancer 26–30 years after I-131 exposure. Further follow-up of the UkrAm cohort would help clarify the dose dependence and long-term temporal pattern of risk. In addition, pooling of data from the UkrAm and parallel Belarusian cohort (BelAm) could improve the precision of risk assessment of thyroid disease after exposure at young ages to I-131 in Chernobyl fallout. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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