Norovirus strains in patients with acute gastroenteritis in rural and low-income urban areas in northern Brazil
| Autor: | Eric Delwart, Maria da Aparecida Rodrigues Teles, Rafael Brustulin, Roozbeh Tahmasebi, Élcio Leal, Alexis Jose-Abrego, Mariana Sequetin Cunha, Flavio Augusto de Pádua Milagres, Vanessa dos Santos Morais, Xutao Deng, Antonio Charlys da Costa, Rory J Tinker, Ester Cerdeira Sabino, Emerson Luiz Lima Araújo, Ramendra Pati Pandey, Adriana Luchs, Mariela Martínez Gómez |
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| Rok vydání: | 2021 |
| Předmět: |
Low income
0303 health sciences Genetic diversity medicine.medical_specialty Phylogenetic tree 030306 microbiology General Medicine Acute gastroenteritis Biology medicine.disease_cause Virology 03 medical and health sciences Medical microbiology Genotype Norovirus medicine In patient 030304 developmental biology |
| Zdroj: | Archives of Virology. 166:905-913 |
| ISSN: | 1432-8798 0304-8608 |
| Popis: | From 2010-2016, a total of 251 stool samples were screened for norovirus using next-generation sequencing (NGS) followed by phylogenetic analysis to investigate the genotypic diversity of noroviruses in rural and low-income urban areas in northern Brazil. Norovirus infection was detected in 19.9% (50/251) of the samples. Eight different genotypes were identified: GII.4_Sydney[P31] (64%, 32/50), GII.6[P7] (14%, 7/50), GII.17[P17] (6%, 3/50), GII.1[P33] (6%, 3/50), GII.3[P16] (4%, 2/50), GII.2[P16] (2%, 1/50), GII.2[P2] (2%, 1/50), and GII.4_New Orleans[P4] (2%, 1/50). Distinct GII.6[P7] variants were recognized, indicating the presence of different co-circulating strains. Elucidating norovirus genetic diversity will improve our understanding of their potential health burden, in particular for the GII.4_Sydney[P31] variant. |
| Databáze: | OpenAIRE |
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