Malignes Lymphom: Magnet- resonanztomographische Befunde bei residuellen supradiaphragmalen raumfordernden Läsionen
| Autor: | G. Spahn, Holger Amthauer, Wolf-Dieter Ludwig, R. Felix, Christian Stroszczynski, N. Hosten, Johannes Hierholzer, Bittner Rc, J. Oellinger |
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| Rok vydání: | 1999 |
| Předmět: |
Pathology
medicine.medical_specialty Chemotherapy medicine.diagnostic_test business.industry medicine.medical_treatment Respiratory disease Mediastinum Magnetic resonance imaging medicine.disease Residual Lymphoma medicine.anatomical_structure medicine Spin echo Radiology Nuclear Medicine and imaging Pectoralis Muscle Nuclear medicine business |
| Zdroj: | RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 171:192-199 |
| ISSN: | 1438-9010 1438-9029 |
| Popis: | PURPOSE Evaluation of MR imaging in patients with Hodgkin's lymphoma and high grade non-Hodgkin's-lymphoma and mediastinal residual mass after first line chemotherapy. MATERIALS AND METHODS MR imaging (1.5 T) was performed in 36 patients (Hodgkin's lymphoma n = 26, NHL n = 10) after first line chemotherapy). Twenty patients had inactive residual mass, 16 patients had residual lymphoproliferative lesions. T1- and T2-weighted spin echo images were visually analysed by a score index (range 1-5) as well as quantification of enhancement by signal-intensity-ratios SImax/SIplain). RESULTS For the differentiation between residual lymphoproliferative activity and inactive residual mass, the highest accuracy was obtained for the signal intensity of residual mass on T2-w-SE compared to pectoralis muscle (94% sensitivity, 80% specificity, likelihood ratios: 4.0 [LR+]; 0.3 [LR-]). The cut-off value of the SI ratio was calculated retrospectively at 1.96 (p > 0.05). CONCLUSIONS Differentiation between inactive (fibrotic) and lymphoproliferative (active) residual mediastinal mass is possible by MR imaging using as parameter the size reduction after therapy and the signal intensity on T2-w-SE in comparison to pectoralis muscle. Thus study suggests an additional value using the SI ratio for the differentiation. |
| Databáze: | OpenAIRE |
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