5,5-Dimethyl-2-phenylamino-2-oxazoline as an effective chiral auxiliary for asymmetric alkylations

Autor:	Thanh Nguyen Le, Taek Hyeon Kim, Jae Nyoung Kim, Quynh Pham Bao Nguyen
Rok vydání:	2007
Předmět:	chemistry.chemical_compound Chiral auxiliary chemistry Organic Chemistry Drug Discovery Organic chemistry Oxazoline Alkylation Biochemistry Valine methyl ester
Zdroj:	Tetrahedron Letters. 48:7834-7837
ISSN:	0040-4039
Popis:	The novel chiral auxiliaries, 5,5-diphenyl-2-phenylamino-2-oxazoline and 5,5-dimethyl-2-phenylamino-2-oxazoline, were prepared from l -valine methyl ester. The 5,5-dimethyl compound was shown to be a particularly effective chiral auxiliary for asymmetric alkylation affording high yields and diastereoselectivities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::292e4db78a0cca9ffa8b1d9ce4fb28a4 https://doi.org/10.1016/j.tetlet.2007.09.001 Zobrazit plný text záznamu Full Text from ScienceDirect