5,5-Dimethyl-2-phenylamino-2-oxazoline as an effective chiral auxiliary for asymmetric alkylations
Autor: | Thanh Nguyen Le, Taek Hyeon Kim, Jae Nyoung Kim, Quynh Pham Bao Nguyen |
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Rok vydání: | 2007 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 48:7834-7837 |
ISSN: | 0040-4039 |
Popis: | The novel chiral auxiliaries, 5,5-diphenyl-2-phenylamino-2-oxazoline and 5,5-dimethyl-2-phenylamino-2-oxazoline, were prepared from l -valine methyl ester. The 5,5-dimethyl compound was shown to be a particularly effective chiral auxiliary for asymmetric alkylation affording high yields and diastereoselectivities. |
Databáze: | OpenAIRE |
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