A comparative study assessing the incidence and degree of hyperkalemia in patients on angiotensin-converting enzyme inhibitors versus angiotensin-receptor blockers
Autor: | Jonathan R. Salik, Thomas H. McCoy, Sara Golas |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Hyperkalemia biology business.industry Incidence (epidemiology) Angiotensin-converting enzyme Health records urologic and male genital diseases medicine.disease female genital diseases and pregnancy complications Internal medicine Internal Medicine medicine biology.protein In patient cardiovascular diseases Angiotensin Receptor Blockers medicine.symptom business Kidney disease |
Zdroj: | Journal of Human Hypertension. 36:485-487 |
ISSN: | 1476-5527 0950-9240 |
Popis: | OVERVIEW Angiotensin-converting enzyme inhibitors (ACEI) and angiotensin-receptor blockers (ARB) are the most commonly prescribed anti-hypertensive medications in the United States, yet whether ACEI or ARB use is associated with a greater risk of hyperkalemia remains uncertain. Using real-world evidence from electronic health records, our study demonstrates that treatment with ACEI is associated with both a higher incidence and greater degree of hyperkalemia than treatment with ARB in adjusted models, especially in patients with chronic kidney disease. Providers should therefore consider this possible difference in hyperkalemia risk when choosing between ACEI and ARB therapy. |
Databáze: | OpenAIRE |
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