Hipoksik iskemik ensefalopatili infantlarda tam kan sayımı parametreleri ve ekokardiyografi bulgularının prognostik değeri
| Autor: | Fatma Durak, Olgu Hallioğlu Kilinç, Gulcin Bozlu, Yalçın Çelik, Dilek Giray, Derya Duman, Baki Kara, Derya Karpuz |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Mitral regurgitation medicine.diagnostic_test business.industry Complete blood count Retrospective cohort study Red blood cell distribution width Regurgitation (circulation) 030204 cardiovascular system & hematology medicine.disease Pulmonary hypertension Hypoxic Ischemic Encephalopathy 03 medical and health sciences 0302 clinical medicine Internal medicine Cardiology General Earth and Planetary Sciences Medicine 030212 general & internal medicine business General Environmental Science Whole blood |
| Zdroj: | Cukurova Medical Journal. 45:119-126 |
| ISSN: | 2602-3032 |
| Popis: | Purpose: The aim of this study was to investigate the prognostic value of complete blood count parameters, presence of pulmonary hypertension (PH) and valve failure in newborns with hypoxic ischemic encephalopathy (HIE). Materials and Methods: 115 term newborns with Sarnat Stage 2 and 3 with HIE and 90 healthy newborns were included in this retrospective study. Echocardiographic examination, red blood cell distribution width (RDW), platelet distribution width (PDW), and C-reactive protein (CRP) values at the first six hours and at 72 hours after the cooling treatment were compared with controls.Results: There was a relationship between presence of mitral regurgitation (MR), aortic regurgitation (AR), and persistent PH and death. The mean RDW, PDW and CRP levels at the first six and after 72 hours were significantly higher in infants with HIE when compared with the control group, and these parameters were significantly increased in the stage 3 group. A significant relationship was found between the increase in RDW and CRP values and the presence of MR, AR and mortality.Conclusion: The degree of PH and presence of valvular insufficiency are important parameters in determining prognosis in HIE. Also, simple blood tests such as RDW and CRP and the echocardiographic evaluation are found to be correlated with hospitalization period and mortality and may be a guide in prognosis. |
| Databáze: | OpenAIRE |
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