Leishmaniose viscérale infantile: un diagnostic difficile en cas d'hémophagocytose associée
| Autor: | M. Radhouane, M.N. Guediche, A. Besbes, M. Bejaoui, A Nadrid, A Khelif, H. Pousse, S Laradi-Chebil |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Pathology business.industry Sodium stibogluconate Leishmaniasis medicine.disease Dermatology Pancytopenia Serology Visceral leishmaniasis medicine.anatomical_structure El Niño Pediatrics Perinatology and Child Health medicine Bone marrow Hemophagocytosis business medicine.drug |
| Zdroj: | Archives de Pédiatrie. 3:881-883 |
| ISSN: | 0929-693X |
| DOI: | 10.1016/0929-693x(96)87578-6 |
| Popis: | Background. — Hemophagocytosis has already been reported in cases of visceral leishmaniasis and thus may complicate search for diagnosis. Case report. — A previously healthy 2 year-old boy was referred for fever and splenomegaly with pancytopenia. An initial diagnosis of kala-azar was refuted because of absence of biological inflammatory syndrome, negativity of bone-marrow aspiration and splenic ponction and of specific serology. After three months of clinical deterioration and apparition of active hemophagocytosis, both bone marrow aspiration and specific serology for visceral leishmaniasis became positive. The boy was given sodium stibogluconate for 20 days; he improved gradually with complete and definitive remission. Conclusion. — Diagnosis of visceral leishmaniasis may be difficult, even in countries where this condition is relatively frequent; the association with hemophagocytosis is possible and does not constitute a poor factor of prognosis if specific therapy is proposed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect