Monoclonal antibodies for immunohistochemical labeling of immunocompetent cells in frozen sections of rhesus monkey tissues

Autor:	A. Timmermans, H. P. J. D. Stevens, N. Stouten, M. Jonker, T. H. Van Der Kwast
Rok vydání:	1991
Předmět:	Pathology medicine.medical_specialty General Veterinary biology medicine.drug_class CD3 chemical and pharmacologic phenomena Monoclonal antibody Staining Antigen MHC class I Monoclonal biology.protein medicine Immunohistochemistry Animal Science and Zoology Antibody
Zdroj:	Journal of Medical Primatology. 20:386-393
ISSN:	1600-0684 0047-2565
DOI:	10.1111/j.1600-0684.1991.tb00557.x
Popis:	Twenty-eight anti-human and two rhesus specific monoclonal antibodies (MAbs) were evaluated for immunohistochemical peroxidase staining reactivity in rhesus monkeys lymph nodes, thymus, liver, and skin allografts. Reactivity with the following antigens was assessed: MHC class I, II-DR, -DQ, and -DP antigens; leukocyte markers CD1, CD2, CD3, CD4, CD8, CD14, CD16, CD25, CD57; a proliferation associated nuclear antigen; interferon-gamma and tumor necrosis factor-alpha. Twenty-three MAbs proved to be suitable for immunohistochemical staining on frozen sections.
Databáze:	OpenAIRE
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