Volumetric modulated craniospinal irradiation workflow optimization through quantitative analytics: a single-institution case study comparing pediatric and adult settings

Autor: Kenneth Wong, Leslie K. Ballas, Julian Sison, Barbara Lam, Nimit Dholakia, Julius K. Weng, Christophe Marques, Eric L. Chang, Steven Nguyen, Arthur J. Olch, Jonathan Waxer
Rok vydání: 2020
Předmět:
Zdroj: Journal of Radiation Oncology. 9:113-121
ISSN: 1948-7908
1948-7894
DOI: 10.1007/s13566-020-00429-9
Popis: We used quantitative analytics to assess the efficiency of the clinical workflow for radiation therapy delivery in children and adults focusing on our experience with volumetric modulated arc therapy (VMAT) craniospinal irradiation (CSI). We retrospectively collected clinical and treatment specific data between June 2013 and November 2018 for 614 VMAT CSI sessions of 41 pediatric patients and 48 VMAT CSI sessions of 6 adult patients treated at two hospitals within the same academic institution. Descriptive statistics were generated and a multiple linear regression model was created to predict total radiation time (TRT) based on these predictors. Prolonged treatment sessions were filtered using the interquartile range outlier detection method for quality assurance review. The median pediatric TRT for all VMAT CSI treatment sessions was 21.07 min (interquartile range (IQR) 9.05). Pediatric patient height, fraction number (fractions 1–3 vs. fractions > 3), and number of isocenters were significant predictors for TRT (p
Databáze: OpenAIRE