P137 Viral hepatitis prevalence among men who have sex with men recruited in an HIV PrEP demonstration study in Cotonou, Benin

Autor: Frédéric Kintin, C Ahouada, Marcel Zannou, Fernand Guédou, A Akpaka, Marlène Aza-Gnandji, Luc Béhanzin, S Ogoundele, Michel Alary, M Goma, Flore Gangbo, A Dossouvo, E Chagas, M Olodo
Rok vydání: 2021
Předmět:
Zdroj: Poster presentations.
Popis: Background Men who have sex with men (MSM) are disproportionally affected by hepatitis worldwide despite the availability of safe and effective vaccines for hepatitis A and B. The aim of this analysis was to estimate the prevalence and risk factors for current and lifetime hepatitis B, and HCV antibodies among MSM in Cotonou. Methods A two-stage cluster sampling procedure was used to recruit 204 MSM in the community-based PrEP demonstration study. First, 7 out of the 13 boroughs in Cotonou were selected using a probability proportional to size method and a fixed number of MSM were then randomly selected from each borough using a random route sampling procedure. A rapid immuno-chromatographic test was used for detecting HBV surface antigen (HBsAg, active infection) and HCV antibodies in whole blood. Enzyme immunoassays were used for detecting HBV core (anti-HBc) and surface (anti-HBs) antibodies (lifetime infection: HBsAg or anti-HBc positivity without anti-HBs). Risk factors analyses controlled for potential confounders using log-binomial regression. Results The prevalence of active and lifetime HBV were 8.8% and 37.7%, respectively. Only two men were HCV-positive (0.98%). Both current (16.7% versus 6.4%, p Conclusion HBV is frequent in this population, especially in older MSM who are more likely to have started their sexual life before the initiation of MSM-specific interventions in Benin (2008). HCV prevalence was low, likely because of the absence of injectable drug use and the fact that all participants were HIV-negative. HBV vaccination, offered free of charge to children in Benin since 2005, should also be systematically offered to MSM susceptible to this infection.
Databáze: OpenAIRE