On Possibility of Optimization of Bone Stress Remodeling in Knee Joint Arthroplasty

Autor:	Turushev M A, Reznik L B, M. A. Turushev, Leonid Borisovich Reznik, L B Reznik
Rok vydání:	2009
Předmět:	medicine.medical_specialty Osteolysis Bone density business.industry medicine.medical_treatment Osteoporosis General Engineering Energy Engineering and Power Technology Knee Joint medicine.disease Arthroplasty Bone remodeling Surgery Strontium ranelate Medicine Implant business medicine.drug
Zdroj:	N.N. Priorov Journal of Traumatology and Orthopedics. 16:19-23
ISSN:	2658-6738 0869-8678
DOI:	10.17816/vto200916419-23
Popis:	Using standard photodensitometry bone remodeling was studied in proximal tibia and distal femur after total knee arthroplasty at terms up to 12 months. Out of 120 patients 60 patients (main group) received strontium ranelate (Bivalos) for 12 months after operation and in 60 patients (control group) drug correction was not performed. By the results of standard photodensitometry in both patient groups the density of radiographic image around the implant decreased by 22% at an average within the first 2 postoperative months and that was indicative of osteolysis activity. Later on during the period from 2 to 6 months after arthroplasty the increase of optic bone density was observed. By the end of 12 month in patients from the main group the optic bone density around the implant increased by 39.6% (to preoperative level) and by 25% in controls as compared with the level recorded in 2 months after surgery. Analysis of the total knee replacement by Lischolm scale showed that drug optimization of the processes of bone tissue remodeling enabled to shorten the terms of patients' rehabilitation and to decrease the rate of unsatisfactory results.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::28a7278581f110e262669076c18e8094 https://doi.org/10.17816/vto200916419-23 Zobrazit plný text záznamu