Perfluoroepoxyoxolanes in the synthesis of fluorine-containing heterocycles

Autor:	A. Ya. Zapevalov, V. I. Saloutin, M. I. Kodess, Pavel A. Slepukhin, T. I. Filyakova
Rok vydání:	2009
Předmět:	chemistry.chemical_compound Quinoxaline Nucleophile Thiourea chemistry Organic Chemistry Organic chemistry Fluorine containing Ring (chemistry) Thiazole Solid carbon dioxide
Zdroj:	Russian Journal of Organic Chemistry. 45:884-889
ISSN:	1608-3393 1070-4280
Popis:	Perfluoro-3,4-epoxyoxolane and 3,4-epoxy-2-trifluoromethylpentafluorooxolane readily reacted with difunctional nucleophiles via opening of the oxirane ring and subsequent heterocyclization. Their reactions with thiourea and o-phenylenediamine gave new fluorine-containing fused heterocyclic compounds, 2-amino-3a-hydroxy-4,4,6,6,6a-pentafluoro-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]thiazole and 1,1,3,3-tetrafluoro- and 1-trifluoromethyl-1,3,3-trifluoro-1,3-dihydrofuro[3,4-b]quinoxalines, respectively. The molecular and crystalline structures of the products were determined by X-ray analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::28922da81734a0f606f9d7ad64596a4a https://doi.org/10.1134/s1070428009060141 Zobrazit plný text záznamu Plný text ve formátu PDF