15. The Effect of Celery (Apium graveolens L.) Leaf Infusion on Blood Cholesterol Levels in White Male Rat (Rattus norvegicus) Induced by Alloxan

Autor: Zuhrawati Na, T. Armansyah Tr, Kiky Moelviani, Rusli Rusli, Sugito Sugito, Roslizawaty Roslizawaty
Rok vydání: 2019
Předmět:
Zdroj: Jurnal Medika Veterinaria. 13:108-113
ISSN: 2503-1600
0853-1943
Popis: This study aimed to determine the effect of celer y (Apium graveolens L.) leaves infusion on blood cholesterol levels in male rats (Rattus norvegicus) induced by alloxan. The sample used in this study were 25 white male rats Wistar strain ed aged 3-4 months with a bodyweight of 150-200 grams. The desig n used are were unidirectional pattern of completely randomized design with 5 treatments and 5 replicat ions . Treatment 1 (P1) rat s were given with the standard feed. Treatment 2 (P2),rats were induced by alloxan. Treatment 3 (P3 ) rats were induced by alloxan and given 2 ml of 5% celery leaf infusion therapy . Treatment 4 (P4) rats were induced by alloxan and given 2 ml of 10% celery leaf infusion therapy . Treatment 5 (P5) rats were induced by alloxan and given 2 ml of 15% celery leaf infusion therapy . Celery leaf infusion was given every morning and evening. Administration of alloxan with a single dose of 150 mg / kg in IP and celery leaf infusion therapy were given for 14 days. Rat blood cholesterol levels checked using the CHOD-PAP. Data were analyzed using ANOVA completely randomized design. Mean (± SD) of cholesterol in treatment P1, P2, P3, P4 and P5 sequence was 52.8 ± 9 . 09; 50.4 ± 18 . 53; 42.6 ± 4 . 51; 40.2 ± 52.8 ± 7 . 19 and 2 . 39. The results showed that the infusion of celery leaves was not show ing any effect (P> 0.05) on blood cholesterol levels of white male rats induced by alloxan. Administration of celery leaves (Apium graveolens L.) infusion for 14 days with a concentration of 5%, 10% and 15% have no effect on blood cholesterol levels in male rats induced by alloxan.
Databáze: OpenAIRE
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