Analysis of factors associated with portal vein thrombosis in pediatric living donor liver transplant recipients
| Autor: | Andre L. Godoy, Gilda Porta, Irene K. Miura, Eduardo A. Fonseca, Mario Kondo, Cristian V. Borges, Adriana Porta, Paulo Chapchap, Marcel R. Benavides, Vera B. Danesi, Joao Seda Neto, Teresa Guimarães, Helry L. Candido, Flavia H. Feier, Renata Pugliese |
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| Rok vydání: | 2014 |
| Předmět: |
Transplantation
medicine.medical_specialty genetic structures Hepatology business.industry medicine.medical_treatment Incidence (epidemiology) Retrospective cohort study Liver transplantation medicine.disease behavioral disciplines and activities Living donor Mesenteric Vein Surgery Portal vein thrombosis mental disorders Cohort medicine Risk factor business human activities |
| Zdroj: | Liver Transplantation. 20:1157-1167 |
| ISSN: | 1527-6465 |
| Popis: | The technique of vascular reconstruction plays a major role in the outcome of living donor liver transplantation (LDLT). An increased use of vascular grafts (VGs) as replacements for sclerotic portal veins has become a standard technique for our group. The aim of this study was to analyze the factors associated with portal vein thrombosis (PVT) in pediatric LDLT. We performed a retrospective analysis of 486 primary pediatric LDLT procedures performed between October 1995 and May 2013. VGs used for portal reconstruction included living donor inferior mesenteric veins, living donor ovarian veins, recipient internal jugular veins, deceased donor iliac arteries, and deceased donor iliac veins. Thirty-four patients (7.0%) developed PVT. The incidence of PVT dropped from 10.1% to 2%; the overall utilization of VGs increased from 3.5% to 37.1%. In a multivariate analysis, only the use of VGs remained an independent risk factor for the occurrence of PVT (hazard ratio = 7.2, 95% confidence interval = 2.8-18.7, P |
| Databáze: | OpenAIRE |
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