Role of sST2 in prognostication and risk stratification in patients with heart failure

Autor:	Bhabani Charan Sahoo, Manjunath Bagur Venkat, Gaurav Pradip Thakre
Rok vydání:	2017
Předmět:	medicine.medical_specialty business.industry medicine.disease Family member Cardiac strain Clinical decision making Heart failure Internal medicine Risk stratification medicine Risk of mortality Cardiology Biomarker (medicine) In patient business
Zdroj:	International Journal of Research in Medical Sciences. 5:2964
ISSN:	2320-6012 2320-6071
DOI:	10.18203/2320-6012.ijrms20172970
Popis:	Background: sST2, an interleukin (IL)-1 receptor family member, has been identified as a novel biomarker for cardiac strain. Concentrations of sST2 have prognostic value and found to be predictive of the rate of mortality in the follow-up of patients after an acute heart failure episode. The present study aims to study relationship between serum sST2 levels along with prognosis and risk of mortality in heart failure patients.Methods: The Study was conducted in A.J. Institute of Medical Sciences, Mangalore, Karnataka, India with 56 heart failure patients in the duration of 1 year. sST2 level of each patient was taken on the day of admission then after one month, six months and one year.Results: Concentration of sST2 was consistently higher in 55.3% patients. Patients with lower values of ST2 levels were having less number of hospital admissions for heart failure symptoms (44.6%). The patients who were having high ST2 levels died due to cardiac events by the end of one month, six months and one year were 7.1%, 11.5% and 13% respectively (p
Databáze:	OpenAIRE
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