The burden of asthma, hay fever and eczema in children in 25 countries: GAN Phase I study

Autor: Luis García-Marcos, M. Innes Asher, Neil Pearce, Eamon Ellwood, Karen Bissell, Chen-Yuan Chiang, Asma El Sony, Philippa Ellwood, Guy B. Marks, Kevin Mortimer, A. Elena Martínez-Torres, Eva Morales, Virginia Perez-Fernandez, Steven Robertson, Charlotte E. Rutter, Richard J. Silverwood, David P. Strachan
Rok vydání: 2022
Předmět:
Zdroj: European Respiratory Journal. 60:2102866
ISSN: 1399-3003
0903-1936
Popis: AimsThere have been no worldwide standardised surveys of prevalence and severity of asthma, rhinoconjunctivitis and eczema in school children for 15 years. The present study aims to provide this information.MethodsFollowing the exact International Study of Asthma and Allergies in Childhood (ISAAC) methodology (cross-sectional questionnaire-based survey), Global Asthma Network (GAN) Phase I was carried out between 2015 and 2020 in many centres worldwide.ResultsThe study included 157 784 adolescents (13–14 years of age) in 63 centres in 25 countries and 101 777 children (6–7 years of age) in 44 centres in 16 countries. The current prevalence of symptoms, respectively, was 11.0% and 9.1% for asthma, 13.3% and 7.7% for rhinoconjunctivitis and 6.4% and 5.9% for eczema. The prevalence of asthma ever was 10.5% and 7.6%, hay fever ever was 15.2% and 11.1% and eczema ever was 10.6% and 13.4%, respectively. Centres in low or lower middle gross national income countries (LICs or LMICs) had significantly lower prevalence of the three disease symptoms and diagnoses (except for hay fever). In children, the prevalence of asthma and rhinoconjunctivitis symptoms was higher in boys, while the reverse occurred among adolescents. For eczema, while the prevalence among female adolescents was double that of males, there was no sex difference among children. Centre accounted for non-negligible variability in all disease symptoms (10–20%).ConclusionThe burdens of asthma, rhinoconjunctivitis and eczema vary widely among the limited number of countries studied. Although symptom prevalence is lower in LICs and LMICs, it represents a considerable burden everywhere studied.
Databáze: OpenAIRE
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