Update in Diabetic Nephropathy

Autor: United Arab Emirates, Abdu Adem, Enyioma N. Obineche
Rok vydání: 2005
Předmět:
Zdroj: International Journal of Diabetes and Metabolism. 13:1-9
ISSN: 2073-5944
1606-7754
DOI: 10.1159/000497567
Popis: Diabetic nephropathy has become the leading cause of end-stage kidney disease worldwide and is associated with an increased cardiovascular risk. The earliest clinical manifestation is microalbuminuria. Tight blood glucose and blood pressure control reduce the risk of microalbuminuria. Once microalbuminuria is present, the rate of progression to end stage kidney disease and cardiovascular disease can be delayed by aggressive management of blood pressure, glucose, and lipids. Inhibition of the reninangiotensin system is important in reducing intraglomerular pressure but other classes of antihypertensive agents may also be needed to obtain adequate control of systemic blood pressure. Such measures can at least reduce by half the rate of progression of nephropathy and cardiovascular disease.
Databáze: OpenAIRE