Lesinurad, a Selective Uric Acid Reabsorption Inhibitor, in Combination With Febuxostat in Patients With Tophaceous Gout: Findings of a Phase III Clinical Trial

Autor:	Fernando Perez-Ruiz, Dinesh Khanna, Graeme Jones, J. Kopicko, Scott Adler, Nicola Dalbeth, Maple Fung, C. Storgard, Robert Terkeltaub, Nihar Bhakta, Scott Baumgartner
Rok vydání:	2017
Předmět:	musculoskeletal diseases congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Immunology Urology Pharmacology Tophaceous gout law.invention 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Rheumatology Randomized controlled trial law medicine Immunology and Allergy In patient 030212 general & internal medicine 030203 arthritis & rheumatology Reabsorption business.industry nutritional and metabolic diseases Lesinurad Clinical trial chemistry Uric acid Febuxostat business medicine.drug
Zdroj:	Arthritis & Rheumatology. 69:1903-1913
ISSN:	2326-5191
DOI:	10.1002/art.40159
Popis:	Objective To investigate the efficacy and safety of lesinurad in combination with febuxostat in a 12‐month phase III trial in patients with tophaceous gout.
Databáze:	OpenAIRE
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