Design of new anticancer drugs. II. Easy arynic access to benzocyclobutacarbazoles, a new family of antitumor agents

Autor:	Pierre Renard, Paul Caubère, Stéphanie Christophe, Catherine Kuehm-Caubère, Bruno Pfeiffer
Rok vydání:	1998
Předmět:	chemistry.chemical_compound chemistry Aryl Organic Chemistry Drug Discovery Condensation Biochemistry Combinatorial chemistry
Zdroj:	Tetrahedron Letters. 39:9431-9434
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(98)02186-8
Popis:	Tetrahydrobenzocyclobutacarbazoles with antitumoral properties were obtained either by arynic condensation of aryl halides with 3-carbazolone enolates or arynic cyclisation of halogenated arylimine enolates of 2-biphenylenones in the presence of the complex base NaNH2-tBuONa.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::28122842fc209250ec97ef5b8ca2ff27 https://doi.org/10.1016/s0040-4039(98)02186-8 Zobrazit plný text záznamu Full Text from ScienceDirect