1-Ethyl-1,4-dihydro-4-oxo-7-(pyridinyl)-3-quinolinecarboxylic acids. I. Synthesis of 3- and 4-(3-aminophenyl)pyridine intermediates

Autor: Chester Joseph Opalka, Roman R. Lorenz, R. Pauline Brundage, George Y. Lesher, Gordon L. Williams, Baldev Singh, William H. Thielking, Philip M. Carabateas, Karl O. Gelotte, Monte D. Gruett
Rok vydání: 1984
Předmět:
Zdroj: Journal of Heterocyclic Chemistry. 21:1849-1856
ISSN: 1943-5193
0022-152X
DOI: 10.1002/jhet.5570210654
Popis: A series of substituted 3- and 4-(3-aminophenyl)pyridines has been prepared as intermediates for the synthesis of some 1-alkyl-1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acids. The Hantzsch, Hauser and other pyridine syntheses were used. 4-(3-Aminophenyl)pyridine was prepared via 3-(4-pyridinyl)-2-cyclohexen-1-one using the Semmler-Wolff reaction.
Databáze: OpenAIRE