Collaborative study on the determination of phencyclidine in urine by gas chromatography-mass spectrometry
| Autor: | Chiareiy Liu, Wen-Ing Tsay, Kuei-Hui Chan, Wei-Lan Chu, Mei-Chich Hsu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pharmacology
0303 health sciences Reproducibility Chromatography 030309 nutrition & dietetics Chemistry 010401 analytical chemistry Relative standard deviation Urine Repeatability Mass spectrometry 01 natural sciences Urine testing 0104 chemical sciences 03 medical and health sciences Gas chromatography–mass spectrometry Food Science |
| Zdroj: | Journal of Food and Drug Analysis. 17 |
| ISSN: | 2224-6614 |
| DOI: | 10.38212/2224-6614.2304 |
| Popis: | A gas chromatography-mass spectrometry method for the analysis of phencyclidine (PCP) in urine was subjected to an inter-laboratory study. The collaborative study followed the guidelines provided by the Association of Official Analytical Chemists International. Ten laboratories participated, analyzing 3 samples of PCP-spiked urine as blind duplicate. The repeatability relative standard deviation (RSD(subscript r)) and the reproducibility relative standard deviation (RSD(subscript R)) were between 2.1%-3.6% and 4.2%-7.3%, respectively. HORRAT values for the reproducibility showed 0.4-0.7, indicating acceptable precision between laboratories. The method was thus proposed to be used by the drug-abuse urine testing laboratories in Taiwan. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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